Researchers at the University of North Carolina have presented a simple test that aims to determine which treatment for cystic fibrosis (CF) will work best for a given patient.
The test uses nanospheroids, “fuzzy balls” that grow from cells taken from inside the noses of CF patients,as samples for drug testing.
“Any given drug may not be the drug that works best for a given patient, because there’s so much variation from person to person,” said Jennifer Guimbellot, MD, who conducted the research at UNC and is now assistant professor of pediatrics at the University of Alabama at Birmingham.
“We still have a long way to go to get a really optimized therapy for most cystic fibrosis patients, and the only way we can do that is to have a model like ours, where we can take cells from each individual patient and test them with each individual drug to find out which one is the best match.”
Source & further reading:http://news.unchealthcare.org/news/2017/november/new-simple-test-could-help-cystic-fibrosis-patients-find-best-treatment
Image: These are nasospheroids that developed from a CF patient's nasal tissue in a dish. UNC researchers are using them to screen the effectiveness of CF treatments.
Source: Corina Marinescu
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