Teixobactin is the first new class of antibiotic announced in decades.
Teixobactin inhibits cell wall synthesis by binding to a highly conserved
motif of lipid II (precursor of peptidoglycan) and lipid III (precursor of cell
wall teichoic acid).
The properties of this compound suggest a path towards developing antibiotics that are likely to avoid development of resistance.
Paper:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14098.html
The properties of this compound suggest a path towards developing antibiotics that are likely to avoid development of resistance.
Paper:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14098.html
Corina Marinescu
No comments:
Post a Comment