Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii, an apicomplexan.[3] Infections
with toxoplasmosis usually cause no obvious symptoms in adults.[2] Occasionally,
people may have a few weeks or months of mild, flu-like illness such
as muscle aches and tender lymph nodes.[1] In
a small number of people, eye problems may develop.[1] In
those with a weak immune system, severe symptoms such as seizures and
poor coordination may occur.[1] If
a woman becomes infected during pregnancy, a condition known as congenital toxoplasmosis may affect the child.[1]
Toxoplasmosis is usually spread by
eating poorly cooked food that contains cysts, exposure to
infected cat feces, and from an infected mother to her baby during pregnancy.[3] Rarely,
the disease may be spread by blood transfusion.[3] It
is not otherwise spread between people.[3] The
parasite is known to reproduce sexually only in the cat family.[8] However,
it can infect most types of warm-blooded animals, including humans.[8] Diagnosis
is typically by testing blood for antibodies or by testing the amniotic fluid in pregnant women for the parasite's DNA.[4]
Prevention is by properly preparing and
cooking food.[9] Pregnant
women are also recommended not to clean cat litter boxes or, if they must, to
wear gloves and wash their hands afterwards.[9] Treatment
of otherwise healthy people is usually not needed.[5] During
pregnancy, spiramycin or pyrimethamine/sulfadiazine and folinic acid may
be used for treatment.[5]
Up to half of the world's population is
infected by toxoplasmosis, but have no symptoms.[7] In
the United States, approximately 11% of people are infected, while in some
areas of the world this is more than 60%.[3] Approximately
200,000 cases of congenital toxoplasmosis occur a year.[6] Charles Nicolle and Louis Manceaux first
described the organism in 1908.[10] In
1941, transmission during pregnancy from a mother to a baby was confirmed.[10] There
is tentative evidence that infection may affect people's behavior.[11]
T. gondii tachyzoites |
|
Causes |
|
Eating poorly cooked food, exposure to
infected cat feces[3] |
|
Blood test, amniotic fluid test[4] |
|
Treatment |
During pregnancy spiramycin or pyrimethamine/sulfadiazine and folinic acid[5] |
Frequency |
Up to 50% of people, 200,000 cases of
congenital toxoplasmosis a year[6][7] |
Source: https://en.wikipedia.org/wiki/Toxoplasmosis
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